Providing The Technology You Need
Our technology covers a broad spectrum of mixing applications; low shear mixers for blending, suspending, and heat transfer, and high shear mixers for difficult dry ingredient incorporation and dispersion, and the mixing of immiscible liquid phases to produce emulsion preparations.
Our sanitary designs meet the rigorous hygienic and safety standards for GMP facilities. Scott Mixers Batch and Inline mixers and milling equipment are constructed of FDA-approved materials and many are 3-A certified and comply with strict cGMP requirements.
These products can be either water-in-oil or oil-in-water emulsions, consisting of waxes, emollients, and lubricants dispersed in the oil phase; a water phase containing emulsifying, stabilizing, and thickening agents, preservatives; and in some cases, colorant.
Active ingredients are dispersed in either phase or added when the emulsion has been formed and allowed to cool.
Use Scott Mixers equipment to:
- Dissolve ingredients
- Create stable emulsions.
- Disperse of dyes and perfumes
Some ingredients are difficult to disperse, creating lumps and fisheyes. Our equipment can disperse ingredients quickly and in ambient temperature water. Our inline mixers ensure all material is uniform prior to being homogenized. Our high shear mixers disperse and emulsify, while low-speed agitators allow for the addition of colors and fragrances.
Traditionally, cough syrups and mixtures are mostly sucrose, maltodextrin, glucose, invert syrup, with the remainder consisting of thickening agents, stabilizers, flavors, colorants, and active ingredients.
Use Scott Mixers equipment to:
- Rapidly add and dissolve sugar
- Disperse and hydrate powdered ingredients
- Blending uniformly
- Provide smooth, agglomerate-free, homogeneous finish
Tablet coatings generally consist of sugar or cellulose-based binder, plasticizer, film-forming agents, and colorant. These ingredients are typically either granulated or powdered.
Use Scott Mixers equipment to:
- Mix dry ingredients including cellulose gum thickeners, lump-free into solution
- Fully dissolve ingredients
- Uniformly disperse color
These solutions typically are formulated with a saline solution and a range of added ingredients, including cellulose gum thickening agents, surfactants, and active ingredients.
Use Scott Mixers equipment to:
- Disperse and hydrate small amounts of ingredients
- Dissolve salts
- Add dry powders
- Precisely add other ingredients
These products may use a hydrated viscosity modifying ingredient to maintain a uniform suspension when the API particles tend to float or settle.
Use Scott Mixers equipment to:
- Disperse and hydrate small amounts of ingredients
- Dissolve salts
- Handle dry powders
Expertise You Expect
Whether developing new formulations, scaling-up to production, or improving your full-scale manufacturing, our technical sales and application experts have the knowledge and experience to engineer a mixing solution to meet your toughest challenges.
Scott Mixers and mixing solutions are backed by equipment Factory Acceptance Testing (FAT), QA, and full validation documentation packages.
Frequently Asked Questions
How do EBARA Mixers brands Scott Mixers and Sharpe Mixers ensure compliance with strict cGMP, FDA, and 3-A sanitary standards in pharmaceutical manufacturing?
The materials in our mixing and milling systems are compliant and certifiable with GMP, FDA, 3-A Sanitary Standards, and other association regulations . We provide the necessary documentation as a turnover package, including all applicable information required to validate the equipment as part of the customer’s end-product manufacturing process.
What mixing technologies do you provide for difficult pharmaceutical dispersions, such as hydrating cellulose gum thickeners or blending tablet coatings?
For challenging dry-ingredient incorporation, Scott Mixers high-shear batch and inline mixers provide the intense mechanical and hydraulic shear necessary to rapidly disperse and hydrate active powders, salts, sugars, and thickeners like cellulose gum. This high-shear action completely eliminates agglomerates and lumps, ensuring a uniform, homogeneous finish. For simpler liquid blending, solids suspension, and heat transfer applications, we offer low-shear mixers designed to maximize efficiency while preserving product integrity.
How does your equipment support predictable scale-up from R&D development to full-scale pharmaceutical production?
EBARA understands that product efficacy and repeatable manufacturing are essential to pharmaceutical safety. Our application experts design equipment with scalable geometric and performance characteristics across our entire lineup, from small-scale lab mixers to full-size inline and batch production systems. This ensures that complex emulsifications, color dispersions, or tablet coating formulations can transition seamlessly from the lab to high-volume manufacturing with predictable, highly repeatable results.
Batch Mixers
Inline Mixers
Delivering the service you deserve
EBARA Mixers has the application experience, expertise, and equipment to provide mixers and system processing equipment you need to make high-quality products, reduce operating costs, improve product quality, and increase profitability.
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Our team provides the most complete and comprehensive portfolio of rotating equipment solutions - mixers and pumps - for your application. We are your perfect process partner.